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Immobilized Human IL-4, premium grade (Cat. No. IL4-H4218) at 5 μg/mL (100 μL/well)can bind Human IL-4 R alpha, Fc Tag (Cat. No. ILR-H5253) with a linear range of 1-20 ng/mL (QC tested).
The purity of Biotinylated Human IL-4 R alpha, Fc,Avitag (Cat. No. ILR-H82F4) is more than 90% and the molecular weight of this protein is around 120-147 kDa verified by SEC-MALS.
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Dupilumab | SAR-231893; REGN-668 | Approved | Sanofi, Regeneron Pharmaceuticals Inc | 达必妥, Dupixent | United States | Prurigo | Regeneron Pharmaceuticals Inc | 2017-03-28 | Hypersensitivity, Immediate; Prostatic Neoplasms; Prurigo; Neurodermatitis; Asthma; Pemphigoid, Bullous; Urticaria; Sinusitis; Pulmonary Disease, Chronic Obstructive; Conjunctivitis, Allergic; Peanut Hypersensitivity; Scleroderma, Localized; Keratoconjunctivitis; Keloid; Dermatitis, Atopic; Eczema; Angioedema; Hypersensitivity; Respiratory Tract Diseases; Eosinophilic gastroenteritis (EG); Meningitis; Pruritus; Alopecia Areata; Chronic Urticaria; Nasal Polyps; Respiration Disorders; Milk Hypersensitivity; Aspergillosis, Allergic Bronchopulmonary; Coronavirus Disease 2019 (COVID-19); Dermatitis; Skin Diseases, Eczematous; Skin Diseases; Genetic Diseases, Inborn; Sleep Apnea Syndromes; Eosinophilic Esophagitis; Rhinitis, Allergic | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Sorafenib Tosylate/MG-K10 | MG-D-1609 | Phase 2 Clinical | Solid tumours | Details | |
| AMG-317 | AMG-317 | Amgen Inc | Details | ||
| QX-005N | QX-005N | Phase 2 Clinical | Qyuns Therapeutics Co Ltd | Chronic Urticaria; Asthma; Prurigo; Sinusitis; Dermatitis, Atopic | Details |
| Elarekibep | PRS-060/AZD1402; PRS-060; AZD-1402 | Phase 2 Clinical | University Of Melbourne, Pieris Pharmaceuticals | Asthma | Details |
| SHR-1819 | SHR-1819 | Phase 2 Clinical | Jiangsu Hengrui Medicine Co Ltd | Asthma; Dermatitis, Atopic | Details |
| Manfidokimab | AK-120 (Akeso ) | Phase 2 Clinical | Zhongshan Akeso Biopharma Co Ltd | Asthma; Dermatitis, Atopic | Details |
| HY-1770 | HY-1770; HY1770; HT-17; HT17 | Phase 1 Clinical | Suzhou Pharmavan Co Ltd | Dermatitis, Atopic; Plaque psoriasis | Details |
| Recombinant anti-IL-4Rα humanized monoclonal antibody (Sansheng Guojian) | 611; 611 Q2W; 611 Q4W | Phase 2 Clinical | Shanghai Cp Guojian Pharmaceutical Co Ltd | Dermatitis, Atopic | Details |
| LQ-036 | LQ-036 | Phase 1 Clinical | Shanghai Novamab Biopharmaceuticals Co Ltd | Asthma | Details |
| BA-2101 | BA-2101; BA2101 | Phase 1 Clinical | Shandong Boan Biotechnology Co Ltd | Nasal Polyps; Chronic Urticaria; Sinusitis; Prurigo; Asthma; Dermatitis, Atopic | Details |
| MG-K10 | MG-K10; MG-010; MG-K-10; BC-005 | Phase 2 Clinical | Dragonboat Biopharmaceutical, Shanghai Mabgeek Biotechnology Co Ltd | Asthma; Dermatitis, Atopic | Details |
| CBP-201 | CBP-201 | Phase 3 Clinical | Suzhou Connect Biopharmaceuticals Ltd | Nasal Polyps; Nose Diseases; Asthma; Sinusitis; Status Asthmaticus; Dermatitis, Atopic | Details |
| CM-310 | CM-310 | Phase 3 Clinical | Keymed Biosciences Co Ltd, CSPC Pharmaceutical Group Ltd | Solid tumours; Pruritus; Nasal Polyps; Nose Diseases; Rhinitis, Allergic; Sinusitis; Asthma; Dermatitis, Atopic | Details |
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